It started when Meyers said he couldn’t believe Gyllenhaal and Reynolds, co-stars of the new space drama Life, were actually BFFs in real life. “People are fascinated by the fact that you two could actually be friends…I think they’re like, “one of them is so upbeat and the other is just this awful, mean guy,” he joked.

Turns out, the pair are Sisterhood of the Traveling Pants-levels of close. Gyllenhaal FaceTimed Reynolds during the show….and even though he didn’t pick up the first time, he called back during a while on a walk with his daughter, Ines.